Psychobiotics for Depression and Anxiety
A clinical trial randomly assigned patients with major depressive disorder to receive either probiotic supplements or placebo for eight weeks. The probiotic consisted of Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium bifidum (2 billion CFUs each). After eight weeks, patients who received the probiotic had significantly decreased total scores on the Beck Depression Inventory, a widely used test to measure the severity of depression, compared with placebo. In addition, they had significant decreases in systemic inflammation as measured by hs-CRP, significantly lower insulin levels, reduced insulin resistance, and a significant rise in glutathione, the body’s master antioxidant.
Other psychobiotics have beneficial consequences on mood and anxiety-like symptoms in people without depressive or anxiety disorders. In a study to investigate the possible effects on anxiety, depression, stress and coping strategies in healthy human volunteers, a probiotic containing Lactobacillus helveticus and Bifidobacterium longum alleviated psychological distress, particularly depression, anger-hostility, and anxiety, and improved problem solving when taken for 30 days. The researchers concluded that L. helveticus and B. longum have beneficial psychological effects in healthy humans.
Psychobiotics can also help boost mood and ease anxiety in people suffering from various chronic diseases. The same probiotic studied above (Lactobacillus casei strain Shirota) was used in another double-blind, placebo-controlled trial in patients with chronic fatigue syndrome.Patients were randomized patients to receive either 24 billion colony forming units of Lactobacillus casei strain Shirota or a placebo daily for two months. The people taking the probiotic had a significant decrease in anxiety symptoms.
Many additional psychobiotics have been shown to treat depression and anxiety in animal studies. Lactobacillus plantarum strain PS128, for example, is known to increase dopamine and serotonin and decrease depression-like behaviors in mice. In depressed mice that have been subjected to early-life stress, this same psychobiotic decreases cortisol, normalizes the stress response system (the HPA axis), and decreases depression.
A new approach to emotional health.Formulated for those seeking to manage their mood and support relaxation.
- Contains the probiotics L.helveticus R0052 and B. longum RO175 in the amounts clinically shown to support mood and relaxation*
- Has 350mg of Organic Ashwagandha and Organic Alaskan Blueberries for stress management*
- Offers digestive and immune system support*
- Made with over 70% organic ingredients—Certified by QCS
- Hypoallergenic, gluten, dairy and soy free, vegetarian
- 2 capsules daily; 60-count
Used in Ayurvedic medicine, Ashwagandha (Withania somnifera) is an adaptogenic herb that helps to restore balance to the body, including supporting a healthy stress response, mood and memory. Additionally, our AuroraBlue Alaskan Blueberry Complex—compared to other wild and cultivated blueberries—contains the highest antioxidant activities (up to 10 times higher) to support brain health and a positive mood.
Adults take 2 capsules daily. May be taken with or without food. Capsules can be opened. Contents can be taken directly with water or raw juices. Not intended for children.
Serving Size: 2 Capsules
Amount Per Serving
Mood Probiotic Blend ... 182mg
Lactobacillus helveticus R0052
Total Lacto Cultures (40 Billion CFU)
Bifidobacterium longum R0175
Total Bifido Cultures (10 Billion CFU)
Total Probiotic Cultures ... 50 Billion CFU
Stess Support Blend ... 350mg
Organic Ashwagandha (root), AuroraBlue® Organic Blueberry Complex [Organic Alaska Blueberry (fruit), Organic Oval-Leaf Blueberry (fruit), Organic ALpine Blueberry (fruit), Organic Dwarf Bilberry (fruit)]
Organic Prebiotic Fiber Blend ... 705mg
Organic Potato [Resistant Starch] (tuber), Organic Acacia Fiber (A.senegal)
Other Ingredients: Non-GMO Vegetable Pullulan (capsule).